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KMID : 0357920040380060430
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Korean Journal of Pathology
2004 Volume.38 No. 6 p.430 ~ p.433
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Isolated Intracranial Rosai-Dorfman Disease -A Case Report-
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Park Jin-Kyu
Cho Mee-Yon
Pyen Jhin-Soo
Park Kwang-Hwa
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Abstract
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Rosai-Dorfman disease (RDD) is an idiopathic histioproliferative disorder of the lymph nodes and extranodal sites. Central nervous system involvement is extremely rare. Intracranial RDD, especially the isolated form, resembles meninigioma both clinically and radiologically. Here, we report a case of isolated, intracranial, dura-based RDD. The patient presented with headache and dizziness with no evidence of lymphadenopathy. Histologically, the lesion consisted of large histiocytes with emperipolesis and lymphoplasma cell infiltrates with a fibrotic background. We discuss the differential diagnosis of this lesion. To our knowledge, this is the first reported Korean case of intracranial RDD.
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KEYWORD
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Rosai Dorfman disease, Meninges, Intracranial
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